Research has found a connection between weight loss drugs such as Ozempic and Zepbound and serious eye conditions, leading to concerns about “Ozempic blindness.” The exact reason for this association is not fully understood, but researchers have put forth a theory.
Despite the popularity of weight loss medications like semaglutide and tirzepatide, they are not without risks. Along with common side effects like nausea and diarrhea, these drugs have been linked to uncommon issues such as gastroparesis and decreased kidney function. Recent studies have uncovered a potential link between these medications and vision problems, prompting some to refer to the phenomenon as “Ozempic blindness.”
A small study published in JAMA Ophthalmology examined data from nine patients who experienced severe vision problems, including sudden blindness, while taking semaglutide (Wegovy, Ozempic) or tirzepatide (Mounjaro, Zepbound). The participants developed conditions such as non-arteritic ischemic anterior optic neuropathy (NAOIN), bilateral papillitis, and paracentral acute middle maculopathy, all affecting vision to varying degrees.
Experts such as Mir Ali, M.D., Christoph Buettner, M.D., Ph.D., and Howard Krauss, M.D., have weighed in on the findings, emphasizing the need for further research to determine if medications like Ozempic and Zepbound are causing these vision issues.
While the link between weight loss drugs and vision problems is not definitive, it raises concerns for individuals considering these medications. Medical professionals advise being aware of the potential risks associated with weight loss drugs and prioritizing vision health.
Individuals with diabetes who were treated with semaglutide had over four times the risk of developing NAION compared to those who did not use the drug. Patients who were overweight or obese were seven times more likely to develop the condition. A recent study has suggested that tirzepatide may also be associated with vision complications related to hyperglycemia. The rapid correction of high blood sugar levels induced by these medications, rather than a toxic effect of the drugs themselves, could potentially lead to ophthalmic issues, according to the study’s authors. Dr. Christoph Buettner, chief of the division of endocrinology at Rutgers Robert Wood Johnson Medical School, notes that swift correction of high blood sugar has previously been linked with eye conditions like retinopathy and papillitis. While both drugs are effective in managing weight and hyperglycemia, improving diabetes and obesity is likely to benefit eye health rather than worsen it.
Dr. Howard Krauss, a surgical neuro-ophthalmologist, emphasizes the importance of investigating the potential links between these medications and vision problems. Although the exact prevalence of vision loss associated with GLP-1s like semaglutide and tirzepatide is unknown, doctors agree that such complications are rare. If individuals experience changes in their vision while taking these medications, Dr. Buettner advises stopping the medication and contacting a healthcare provider promptly. Patients considering these medications should discuss the pace of weight loss and blood sugar management with their doctor to minimize the risk of eye issues. Adjusting the dose or rate of weight loss can help reduce the likelihood of complications.
While serious vision complications are uncommon with these medications, monitoring any changes in vision and communicating with a healthcare provider are crucial for early detection and management.
If you experience any adverse effects or symptoms while taking tirzepatide, it is important to contact your doctor as soon as possible for further evaluation and guidance. Additionally, you may be interested in exploring the potential benefits of incorporating apple cider vinegar into your routine for weight loss. To enhance your makeup routine and achieve a transformational look, consider implementing Bobbi Brown’s top tips specifically tailored for women over 50.
