A recent study published in The Lancet Oncology suggests that women undergoing hormone therapy for menopause symptoms may face an increased risk of breast cancer. The study revealed that the combination of estrogen and progesterone raises the risk of breast cancer in women under 55 with a uterus, while estrogen alone decreases the risk. Dr. Céline Gounder, a medical contributor for CBS News, explained that the study participants, all under 55, were split into two groups based on whether they had a uterus or not, as they require different treatment approaches.
For women with a uterus, the combination of estrogen and progesterone is necessary to prevent thickening of the uterine lining, which could lead to endometrial cancer. On the other hand, women without a uterus can safely take estrogen alone. The study highlighted that estrogen alone reduces the risk of breast cancer, while adding progesterone may slightly increase the risk. This research underscores the evolving nature of science and aims to provide more accurate information on hormone therapy for menopausal women.
Contrary to previous studies like the Women’s Health Initiative, which raised safety concerns and caused misunderstandings about hormone therapy, current research focuses on women who start treatment closer to the onset of menopause. Healthcare professionals now generally consider hormone replacement therapy to be safe and effective for managing menopausal symptoms. However, like any medication, hormone therapy carries certain risks, including an increased risk of heart disease, stroke, blood clots, and some cancers.
The latest study emphasizes the importance of considering the timing and type of hormone therapy for optimal outcomes. It is crucial for individuals to consult with their doctors, taking into account family history and individual factors when deciding on treatment options. Gounder stressed the significance of discussing treatment options with healthcare providers to determine the most suitable approach tailored to each person’s needs.
