WASHINGTON (AP) — A recent study has shown promising results for individuals with muscle-destroying diseases through the use of a revolutionary implant that stimulates the spinal cord. Three participants with a debilitating condition experienced improved muscle function, enabling them to stand and walk more easily.
Researchers revealed that this spinal cord stimulation, initially designed for paralysis, could potentially benefit patients with neurodegenerative diseases like spinal muscle atrophy. The study, led by Marco Capogrosso from the University of Pittsburgh, demonstrated significant improvements in muscle strength and function over a month-long period.
Spinal muscle atrophy is a genetic disorder that gradually deteriorates motor neurons in the spinal cord, resulting in muscle weakness and wasting. While there is currently no cure for this condition, the implant offered a glimmer of hope by activating dormant nerves and enhancing muscle movement.
The participants showed enhancements in muscle strength, fatigue, range of motion, and walking distance with just a few hours of spinal stimulation per week. Despite not achieving normal movement, all three individuals experienced notable progress, including increased walking distance and improved gait patterns.
One participant, Doug McCullough, shared his excitement about the unexpected improvements, emphasizing the surreal benefit of seeing progress in a degenerative disease. Although the effects of the stimulation diminished after the study concluded, participants reported enduring benefits, such as reduced fatigue and enhanced mobility.
While the study is still in its early stages, the findings offer a promising outlook for individuals with muscle diseases. Researchers are optimistic about the potential of spinal cord stimulation in improving muscle function and quality of life for patients with conditions like spinal muscle atrophy.
A concise yet significant proof of concept was described as important by a researcher. She suggested that testing the technique against various muscle-degenerating diseases would be a logical step. “Human spinal circuitry is highly intricate – it’s more than just a collection of reflexes controlled by the brain,” stated Harkema, who is now affiliated with the Kessler Foundation, a nonprofit organization focused on rehabilitation research. She further added, “This study is very robust and makes a valuable contribution to progress.” Meanwhile, at Pitt, Capogrosso mentioned that several small but longer studies are in progress.
The Associated Press Health and Science Department is supported by the Howard Hughes Medical Institute’s Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP remains solely accountable for all content.
