The use of common treatments such as over-the-counter antiviral medication and preventive measures like vaccines may be associated with a decreased risk of dementia. This information was originally featured on Medical News Today. A recent systematic review indicated that anti-inflammatory drugs like ibuprofen, antibiotics, antiviral medications, and vaccines could potentially lower the risk of developing dementia. However, further research is necessary to understand how these drugs can be repurposed for dementia treatment. The review, conducted by researchers from the University of Cambridge and the University of Exeter, analyzed data from 14 studies involving over 130 million individuals and 1 million dementia cases. Results showed that antimicrobials, vaccinations, and anti-inflammatory drugs were linked to a reduced risk of dementia, while vitamins, supplements, antipsychotics, and diabetes medications were associated with a potential increased risk. The findings also suggested varying impacts of antidepressants and certain blood pressure medications. The authors acknowledged limitations in the study and highlighted the need for more consistent evidence on specific drugs that could modify the risk of dementia. Dr. Emer MacSweeney, CEO and consultant neuroradiologist at Re:Cognition Health, emphasized the importance of conducting large-scale, longitudinal, randomized controlled trials to establish a causal relationship between dementia risk and prescription drugs. She also stressed the significance of considering genetic and lifestyle factors, as well as using biomarkers to measure the biological effects of medications.
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