Chelsea Handler discussed her support for “natural drugs” during an appearance on Jimmy Kimmel Live!. The comedian explained her interest in micro-dosing, emphasizing the positive effects of substances like psilocybin and LSD in treating depression and enhancing experiences. Handler shared her experiences of offering drugs at the Vanity Fair Oscars party, highlighting her responsible approach. She also mentioned celebrating her 50th birthday by skiing in a bikini after taking LSD, emphasizing that micro-dosing enhances experiences. Handler’s comments were made in connection with her latest book, I’ll Have What She’s Having.